Principal Scientist, Pharmacology

Principal Scientist, Pharmacology & Bioanalytics - CNS Principal Scientist, Pharmacology & Bioanalytics - CNS 2 days ago Be among the first 25 applicants Get AI-powered advice on this job and more exclusive features. This range is provided by Hamlyn Williams. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Base pay range $180,000.00/yr - $195,000.00/yr Direct message the job poster from Hamlyn Williams Hamlyn Williams is exclusively partnered with a well-funded stealth biotech in LA, looking for a Principal Scientist, heavily involved in the in vivo space, sepcifically in the CNS/Neurodegenerative arena. The key focus for this individual is to drive IND-enabling studies and support the advancement of our CNS-targeted therapeutic programs. Key Responsibilities: Support the design and execution of in vivo pharmacology studies to support discovery and IND-enabling research. Oversee bioanalytical strategy, including quantitative assays such as ELISA, MSD, qPCR, LC/MS, and histological methods to evaluate biodistribution, exposure, and pharmacodynamics. Serve as a key scientific lead in interactions with CROs, academic collaborators, and internal stakeholders. Collaborate cross-functionally to ensure alignment with development goals. Interpret data from preclinical studies and contribute to regulatory submissions, including IND packages. Manage and mentor junior scientists or research associates. Contribute to strategic planning for CNS programs, including evaluation of drug delivery platforms and therapeutic opportunities. Qualifications: Ph.D. in pharmacology, neuroscience, bioengineering, or a related field, with 8+ years of relevant industry experience. Extensive experience in drug development across discovery, preclinical, and IND-enabling stages Proven track record of IND-enabling study execution and data integration. Strong experience with large-molecule therapeutics (e.g., antibodies, oligonucleotides, peptides) in in vivo models. Deep understanding of bioanalytical techniques and their application in PK/PD and biodistribution studies. Experience in CNS drug delivery or CNS disease models is strongly preferred. Demonstrated ability to manage and mentor scientific staff. Excellent communication, organizational, and leadership skills. Salary varies based on experience and level, we are targeting between $160k - 200k base before bonus, 401k and benefits. Seniority level Seniority level Mid-Senior level Employment type Employment type Full-time Job function Job function Science Industries Pharmaceutical Manufacturing and Biotechnology Research Referrals increase your chances of interviewing at Hamlyn Williams by 2x Inferred from the description for this job Vision insurance Medical insurance 401(k) Get notified when a new job is posted. Sign in to set job alerts for “Clinical Nurse Specialist” roles. Murrieta, CA $76,270.00-$125,920.00 1 month ago Long Beach, CA $101,000.00-$227,000.00 1 month ago Los Angeles, CA $92,000.00-$203,000.00 3 weeks ago Registered Nurse - Behavioral Health Assistant Manager San Pedro, CA $60,000.00-$118,000.00 3 days ago San Pedro, CA $60,000.00-$118,000.00 3 weeks ago Ambulatory Care Center Registered Nurse (RN) Registered Nurse (RN) - FT Days - $7,500 Sign on Bonus New Grad Registered Nurse (RN), PIH Health Good Samaritan Hospital, October 6, 2025 Cohort Los Angeles, CA $80,000.00-$95,000.00 2 weeks ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI. #J-18808-Ljbffr